Workshop The Role of Oxygen in Radiation Therapy  Date: September 4-5 2023  Venue: Swedish Academy of Sciences, Stockholm, Sweden

Entrance to KVA possible from 08:30

Speakers: please bring your presentation on USB sticks and deliver to the IT operator before your session


Introductory lecture

09:00-09:30 Introduction to the Workshop Iuliana Toma-Dasu and  Joao Seco


Session 1 – Modelling the Oxygen Effect in Radiation Therapy

Chairperson: Emely Kjellsson Lindblom

 09:30-10:00 Compartment Models for modelling the oxygen impact in RT  Joe Deasy


10:00 – 10:30 Coffee break

10:30-11:00 Monte Carlo and continuous models to describe radiation response of tissue for variable oxygenation
                     levels Emanuele Scifoni

11:00-11:30 Historical review of radiobiology models used to describe the role of hypoxia in RT Loredana Marcu

11:30-12:00 Impact of variable oxygen levels in kill-painting with charged particle therapy Walter Tinganelli

12:00-12:30 General discussion – Session 1 All speakers


12:30-13:30 Lunch break


Session 2 - Oxygenation measurements and modelling of O2 transport

Chairperson: Iuliana Toma-Dasu

13:30-14:00 In-vivo measurement of the oxygenation during FLASH and Conventional RT Brian Pogue

14:00-14:30 Electron paramagnetic resonance (EPR) studies of oxygen effect during radiation
                     therapy Bernard Gallez

14:30-15:00 In-vitro measurements and modelling O2 transport within the cell and impact of cellular response
                     to RT Joao Seco

15:00-15:30  General discussion – Session 2 All speakers


15:30-16:30 Coffee break


Session 3 - Molecular aspect of tissue oxygenation

Chairperson: Joao Seco

16:30-17:00 Molecular markers for tumour hypoxia Ejung Moon

17:00-17:30  Immune-/vascular response with/without O2 and the effect on tumour contro Susanta Hui

18:00-21:30: Conference dinner at the Club Villa of KVA (same venue). Food will be served at 18:00.



Monday 4 September Tuesday 5 September

Entrance to KVA possible from 08:30

Speakers: please bring your presentation on USB sticks and deliver to the IT operator before your session


Session 4 – Oxygen and FLASH

Chairperson: Joao Seco

09:00-09:30 Impact of O2 during FLASH and Conventional RT Pierre Montay-Gruel

09:30-10:00 FLASH effect ON oxygenated and hypoxic tumours - a differential effect demonstrating better
                      tumour control with FLASH for hypoxic tumours Ron Leavitt

10:00-10:30 General discussion – Session 4 All speakers


10:30 – 11:00 Coffee break


Session 5 - Strategies to overcome tumour hypoxia

Chairperson: Emely Kjellsson Lindblom

11:00-11:30 Dose painting accounting for oxygenation Iuliana Toma-Dasu

11:30-12:00 SBRT/SRS treatments versus tumour hypoxia David Carlson


12:00-13:30 Lunch break


Session 6 - Strategies to overcome tumour hypoxia (cont.)

Chairperson: Iuliana Toma Dasu

13:30-14:00 Oxygen substitutes as radiosensitisers Morten Busk

14:00-14:30 Hyperthermia against tumour hypoxia Michael Horsman


14:30-15:00 Coffee break


15:00-15:30 Immune-/vascular response with/without O2 and the effect on tumour control Susanta Hui

15:30-16:00 General discussion - session 6

16:00-16:30 Conclusion remarks from Organizers


End of the meeting

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